SURVEILLANCE OF MULTIDRUG-RESISTANT UROPATHOGENIC ESCHERICHIA COLI IN HOSPITALIZED PATIENTS AND COMMUNITY SETTINGS IN THE SOUTH OF LEBANON

Authors

Nourhan Darwich, Infection Control Graduate, Master Student, Infection Control, Faculty of Health Sciences, Beirut Arab University, Beirut, LebanonFollow
Ali Samaha, Assistant Professor, Department of Biomedical Sciences, Lebanese International University, Beirut, LebanonFollow
Hanan Al Nuqaidan, Head of Studies and Information Office, Nursing Department, Ministry of Health, Kuwait, KuwaitFollow
Ahmad Tassi, Assistant Professor, Nursing Department, Faculty of Health Sciences, Beirut Arab University, Beirut, LebanonFollow
Mirna Fawaz, Associate Professor, Nursing Department, Faculty of Health Sciences, Beirut Arab University, Beirut, LebanonFollow

Keywords

Urinary tract infection, Escherichia coli, Multidrug resistance, Antimicrobial resistance.

Disciplines

Life Sciences | Medicine and Health Sciences

Abstract

Urinary Tract Infection (UTI) is one of the common infectious diseases in both hospitals as well as community settings; they are recognized to be among the most serious worldwide bacterial infections impacting 150 million people globally every year. The purpose of this study was to assess the changing antibiotics resistance profile for uropathogenic Escherichia coli isolated from community and hospital setting over a period of time (2018–2019) with a special emphasis on ESBL/MDR producing Escherichia coli. A descriptive retrospective study was conducted among patients with uropathogenic Escherichia coli from both community and hospital settings in south Lebanon. Out of 863 patients with positive uropathogenic Escherichia coli, 451 (52.25 %) comes from the community while 412 (47.74 %) came from the hospital settings. Almost 60.83 % are not Extended Spectrum Beta-Lactamases (ESBL), 31.4 % ESBL, and 7.76 % Multiple drug resistance (MDR). The majority of urinary tract infections are related to the female population (78.21 %). The most vulnerable age for both gender to develop UTI belong to elderly population (>64 years) which account 37.19 % of all isolates. Statistically, we observed a high resistance rate toward all antibiotics using in the treatment of urinary tract infections such as Cefixime (45.30 %), Sulfamethoxazole (44.95 %), Ciprofloxacin (38.23 %) and Augmentin (38.93 %). A statistically significant association was observed between risk factors for hospitalized patients and all age categories with (P < 0.05). Susceptibility profiles are critical to be evaluated in countries such as Lebanon where excessive use of antibiotics is observed at all levels. Therefore, this finding is useful for the determination of appropriate antimicrobial treatment in UTI patients that are caused by Escherichia coli and to follow the antimicrobial stewardship program to reduce the rate of resistance toward antibiotics.

Recommended Citation

Darwich, Nourhan; Samaha, Ali; Al Nuqaidan, Hanan; Tassi, Ahmad; and Fawaz, Mirna (2020) "SURVEILLANCE OF MULTIDRUG-RESISTANT UROPATHOGENIC ESCHERICHIA COLI IN HOSPITALIZED PATIENTS AND COMMUNITY SETTINGS IN THE SOUTH OF LEBANON," BAU Journal - Health and Wellbeing: Vol. 3: Iss. 1, Article 5.
DOI: https://doi.org/10.54729/2789-8288.1051