EFFECTIVENESS OF PLATELET- RICH FIBRIN WITH BETA TRI-CALCIUM PHOSPHATE PLUS CALCIUM SULFATE ON PERIODONTAL INTRABONY DEFECT MANAGEMENT (RANDOMIZED CONTROLLED CLINICAL STUDY)

Authors

Nancy Traboulsi, Resident in Periodontology Masters Program, Faculty of Dentistry, Beirut Arab University, Beirut, LebanonFollow
Essam Osman, Professor of Dental Biomaterials, Faculty of Dentistry, Beirut Arab University, Beirut, LebanonFollow
Nayer Abo Elsaad, Professor of Periodontology, Faculty of Dentistry, Beirut Arab University, Beirut, LebanonFollow

Keywords

Intrabony defects, Platelet rich fibrin, Bone graft, Beta tri-calcium phosphate, calcium sulfate

Disciplines

Oral and Maxillofacial Surgery | Periodontics and Periodontology

Abstract

The purpose of this study is to evaluate the effectiveness of beta tri-calcium phosphate plus calcium sulfate mix, with or without platelet rich fibrin in reducing probing periodontal pockets clinically and defect depths radiographically, while increasing clinical attachment levels to reconstruct intrabony defects in human clinical trials. Materials and Methods: Sixteen participants with periodontal intrabony defects ≥ 5 mm were divided into two equal groups. The first eight intrabony defects in study group received platelet rich fibrin mixed with EthOss ®; while the eight remaining intrabony defects in control group were reconstructed only with EthOss® synthetic bone substitute. Freidman ANOVA and Mann-Whitney tests were chosen for intra-group and inter-group comparisons, respectively. Results: Final outcomes revealed statistically significant decrease in periodontal pocket depth and defect depth values (P ˂ 0.05) with a statistically significant clinical attachment level gain in study and control groups. Precisely, mean values of all measured categories were greater in study rather than control group participants, as confirmed clinically by William’s probe and radiographically by cone-beam computed tomography at 6 months after surgery. Conclusion: Adding PRF to β-TCP plus CS is highly effective in inducing new periodontal soft and hard tissue synthesis resulting in better clinical and radiographic outcomes when surgically incorporated in periodontal intrabony defect(s).

Author ORCID Identifier

Nancy Traboulsi- https://orcid.org/ 0000-0003-2586-1774

Essam Osman- https://orcid.org/0000-0002-9408-6487

Nayer Abo Elsaad -https://orcid.org/0000-0002-6651-6873

Recommended Citation

Traboulsi, Nancy; Osman, Essam; and Abo Elsaad, Nayer (2022) "EFFECTIVENESS OF PLATELET- RICH FIBRIN WITH BETA TRI-CALCIUM PHOSPHATE PLUS CALCIUM SULFATE ON PERIODONTAL INTRABONY DEFECT MANAGEMENT (RANDOMIZED CONTROLLED CLINICAL STUDY)," BAU Journal - Creative Sustainable Development: Vol. 4: Iss. 1, Article 8.
DOI: https://doi.org/10.54729/RCMT2642

ISSN

2789-8334